HitPredict

Interactor 1: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Interactor 2: HDAC5 (Q9UQL6)
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)
Gene: HDAC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12150997
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006954 - inflammatory response
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 693 Hs			1 1122
+	Hs
		1038759 TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		177391 TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Mm
		1157748 SYNJ1_MOUSE (54-505): 6.76e-11: 67.8: 10.26		HDAC4_MOUSE (1-1103): 0: 651: 53.34
+	Mm
		88461 D3Z656_MOUSE (234-663): 1.16e-10: 67.5: 10.99		HDAC4_MOUSE (1-1103): 0: 651: 53.34
+	Hs
		847111 SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81		HDAC9_HUMAN (25-1055): 0: 608: 56.33
+	Mm
		140261 SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52		HDAC1_MOUSE (673-1103): 1.61e-153: 468: 21.16
+	Mm
		936385 SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52		HDAC2_MOUSE (680-1113): 4.65e-153: 467: 21.68
+	Mm
		1111964 SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52		HDAC9_MOUSE (25-633): 3.61e-142: 442: 47.10
+	Mm
		292413 SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52		HDAC3_MOUSE (679-1119): 4.07e-144: 441: 21.57
+	Dm
		631303 BRM_DROME (165-665): 1e-43: 172: 12.74		Q7KTS4_DROME (681-1119): 6.09e-143: 439: 22.08
+	Hs
		846768 SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		846833 SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		257609 ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		257678 ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		203227 SYNJ1_HUMAN (303-658): 3.22e-09: 62.5: 9.55		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		846962 SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		847037 SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		177241 SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Hs
		980012 IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28		HDAC6_HUMAN (599-1061): 7.06e-106: 362: 31.97