HitPredict

Interactor 1: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Interactor 2: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	28514442, 24981860, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0010467 - gene expression
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 486
+	Hs
		131406 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		MECP2_HUMAN (1-486): 5.16e-113: 344: 100.00
+	Hs
		134818 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88
+	Hs
		328516 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88
+	Hs
		328517 IMA5_HUMAN (3-521): 4.55e-135: 403: 45.46		MBD3_HUMAN (93-249): 3.06e-43: 156: 26.88
+	Hs
		853742 IMA5_HUMAN (3-521): 4.55e-135: 403: 45.46		MBD2_HUMAN (75-249): 3.32e-38: 146: 28.65
+	Hs
		168647 IMA6_HUMAN (1-521): 7.28e-137: 408: 46.75		NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06
+	Hs
		853625 IMA5_HUMAN (3-521): 4.55e-135: 403: 45.46		NIPBL_HUMAN (72-455): 1.96e-09: 62.4: 14.06