HitPredict

Interactor 1: TMOD3 (Q9NYL9)
Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Gene: TMOD3

Interactor 2: SCIN (Q9Y6U3)
Scinderin (Adseverin)
Gene: SCIN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Gelsolin~Tropomodulin
Common GO terms	GO:0003779 - actin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 352 Hs			1 715
+	Hs
		1349411 TMOD2_HUMAN (1-352): 7.98e-135: 389: 75.85		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		657569 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		414084 TMOD3_HUMAN (1-352): 1.04e-142: 409: 100.00		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		414088 TMOD2_HUMAN (1-352): 7.98e-135: 389: 75.85		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413834 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		1023245 TMOD3_HUMAN (1-352): 1.04e-142: 409: 100.00		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		657487 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		1023247 TMOD4_HUMAN (4-346): 1.14e-126: 368: 55.10		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		313893 TMOD3_HUMAN (1-352): 1.04e-142: 409: 100.00		SVIL_HUMAN (21-347): 1.62e-31: 134: 21.73
+	Hs
		313758 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		SVIL_HUMAN (21-347): 1.62e-31: 134: 21.73
+	Hs
		260677 TMOD2_HUMAN (1-352): 7.98e-135: 389: 75.85		AVIL_HUMAN (44-539): 1.91e-23: 108: 18.37