HitPredict

Interactor 1: GGA3 (Q9NZ52)
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)
Gene: GGA3

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 723 Hs			1 1620
+	Hs
		666656 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		434297 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		601604 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		FGFR2_HUMAN (952-1433): 9.52e-123: 407: 25.24
+	Hs
		665436 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		EPHA3_HUMAN (943-1427): 7.27e-120: 404: 25.87
+	Hs
		508231 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		435783 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		276988 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		508257 GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		385624 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1081629 GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		277002 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		FGFR2_HUMAN (952-1433): 9.52e-123: 407: 25.24
+	Hs
		277011 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		EPHA3_HUMAN (943-1427): 7.27e-120: 404: 25.87
+	Hs
		277004 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		FGFR3_HUMAN (952-1449): 6.42e-121: 401: 26.31
+	Hs
		276996 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Rn
		88616 D3ZHG8_RAT (1-723): 6.55e-121: 378: 67.08		NTRK1_RAT (1111-1390): 1.4e-63: 235: 42.71
+	Hs
		385689 GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		241132 TOM1_HUMAN (7-402): 8.19e-85: 278: 22.76		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		277074 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		NTRK2_HUMAN (1093-1375): 7.35e-64: 236: 41.44
+	Hs
		276985 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		277073 STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03