HitPredict

Interactor 1: IL37 (Q9NZH6)
Interleukin-37 (IL-37) (FIL1 zeta) (IL-1X) (Interleukin-1 family member 7) (IL-1F7) (Interleukin-1 homolog 4) (IL-1H) (IL-1H4) (Interleukin-1 zeta) (IL-1 zeta) (Interleukin-1-related protein) (IL-1RP1)
Gene: IL37

Interactor 2: IRPL1 (Q9NZN1)
Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (EC 3.2.2.6) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1)
Gene: IL1RAPL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25654981
Identification Methods	solid phase assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IL1~ig, IL1~Ig_6
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 696
+	Hs
		1035370 IL37_HUMAN (1-218): 2.16e-119: 339: 100.00		IL18R_HUMAN (10-570): 1.46e-74: 252: 26.18
+	Hs
		353016 IL1B_HUMAN (45-206): 3.98e-53: 173: 25.61		IL1AP_HUMAN (8-570): 7.22e-95: 306: 31.19
+	Hs
		540381 IL1RA_HUMAN (53-204): 8.9e-56: 177: 27.74		IL1R1_HUMAN (47-588): 2.53e-84: 278: 25.23
+	Hs
		352979 IL1B_HUMAN (45-206): 3.98e-53: 173: 25.61		IL1R1_HUMAN (47-588): 2.53e-84: 278: 25.23
+	Mm
		499359 IL1B_MOUSE (60-206): 3.06e-46: 155: 27.52		ILRL1_MOUSE (11-582): 1.49e-87: 287: 23.38
+	Mm
		499358 IL1B_MOUSE (60-206): 3.06e-46: 155: 27.52		IL1R1_MOUSE (1-586): 7.64e-84: 277: 24.71
+	Hs
		609581 IL37_HUMAN (1-218): 2.16e-119: 339: 100.00		FGFR3_HUMAN (92-376): 3.16e-17: 87.9: 19.70
+	Hs
		577479 IL1RA_HUMAN (53-204): 8.9e-56: 177: 27.74		IL1R2_HUMAN (9-383): 5.71e-66: 224: 22.40
+	Hs
		352988 IL1B_HUMAN (45-206): 3.98e-53: 173: 25.61		IL1R2_HUMAN (9-383): 5.71e-66: 224: 22.40