HitPredict

Interactor 1: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Interactor 2: RBM8A (Q9Y5S9)
RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A)
Gene: RBM8A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0005829 - cytosol GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 174
+	Hs
		128353 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		RBM8A_HUMAN (1-169): 1.46e-41: 138: 100.00
+	Hs
		128007 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		128165 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		1031481 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		516722 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		128177 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		128342 IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85		PPIE_HUMAN (74-160): 1.75e-17: 79.4: 31.03
+	Hs
		1054631 IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Xl
		251139 IF23A_XENLA (1-577): 1.61e-140: 421: 73.06		EPABA_XENLA (64-158): 3.2e-22: 94.1: 20.00
+	Hs
		516531 PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		1054332 PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	At
		1323581 Q9FNK3_ARATH (185-560): 7.33e-29: 123: 14.84		ORRM2_ARATH (47-169): 6.67e-28: 103: 25.20
+	Hs
		1031509 IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		516769 IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		1031431 FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25		PABP4_HUMAN (64-158): 1.4e-23: 98.4: 23.16
+	Hs
		516642 FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		963587 IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84		TIAR_HUMAN (66-164): 4.25e-20: 87.3: 20.20
+	Hs
		963561 FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25		TIAR_HUMAN (66-164): 4.25e-20: 87.3: 20.20
+	Hs
		1054722 IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		680479 FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25		TIA1_HUMAN (68-162): 8.55e-20: 86.8: 24.21