HitPredict

Interactor 1: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Interactor 2: RGPD4 (Q7Z3J3)
RanBP2-like and GRIP domain-containing protein 4
Gene: RGPD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 521 Hs			1 1758
+	Hs
		63862 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RGPD3_HUMAN (1-1758): 0: 2400: 98.29
+	Hs
		152769 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		RGPD8_HUMAN (1-1758): 0: 2363: 95.05
+	Hs
		853440 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		RGPD5_HUMAN (1-1758): 0: 2360: 95.05
+	Hs
		134964 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RANB3_HUMAN (979-1492): 1.92e-38: 155: 15.16
+	Hs
		134854 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RBP2_HUMAN (785-1199): 6.94e-36: 152: 25.68
+	Hs
		134978 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		NUP50_HUMAN (833-1170): 6.44e-37: 148: 16.84
+	Hs
		134843 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		RANG_HUMAN (1015-1208): 1.13e-38: 145: 37.37
+	Hs
		131404 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		RBP2_HUMAN (785-1199): 6.94e-36: 152: 25.68
+	Hs
		131527 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		NUP50_HUMAN (833-1170): 6.44e-37: 148: 16.84
+	Hs
		131396 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		RANG_HUMAN (1015-1208): 1.13e-38: 145: 37.37
+	At
		1280910 IMPA1_ARATH (1-521): 3.44e-158: 462: 43.72		NU50A_ARATH (791-1196): 1.16e-28: 123: 18.75
+	At
		97810 IMPA2_ARATH (1-521): 1.4e-157: 461: 44.69		NU50A_ARATH (791-1196): 1.16e-28: 123: 18.75
+	Hs
		834693 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		RBP2_HUMAN (785-1199): 6.94e-36: 152: 25.68
+	At
		285384 IMPA4_ARATH (1-521): 2.9e-155: 455: 41.64		NU50A_ARATH (791-1196): 1.16e-28: 123: 18.75
+	Hs
		853515 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		NUP50_HUMAN (833-1170): 6.44e-37: 148: 16.84
+	Hs
		1192291 Q7Z726_HUMAN (1-521): 1.97e-145: 429: 49.62		NUP50_HUMAN (833-1170): 6.44e-37: 148: 16.84
+	Sc
		691660 IMA1_YEAST (2-521): 1.2e-140: 417: 44.90		NUP2_YEAST (766-1172): 1.22e-38: 158: 17.26
+	At
		1320502 IMPA6_ARATH (1-521): 2.38e-153: 450: 43.41		NU50A_ARATH (791-1196): 1.16e-28: 123: 18.75
+	At
		138100 IMPA3_ARATH (1-521): 7.35e-152: 446: 43.55		NU50A_ARATH (791-1196): 1.16e-28: 123: 18.75
+	Hs
		238747 IMA7_HUMAN (1-521): 3.56e-142: 421: 46.46		NUP50_HUMAN (833-1170): 6.44e-37: 148: 16.84