HitPredict

Interactor 1: CNOT2 (Q9NZN8)
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Gene: CNOT2

Interactor 2: TNR6B (Q9UPQ9)
Trinucleotide repeat-containing gene 6B protein
Gene: TNRC6B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	29395067, 21981923
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031047 - regulatory ncRNA-mediated gene silencing
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 540 Hs			1 1833
+	Hs
		257428 CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19		TNR6B_HUMAN (28-1833): 0: 1086: 100.00
+	Mm
		1206839 CNOT3_MOUSE (4-524): 3.42e-109: 344: 17.14		TNR6B_MOUSE (28-1833): 0: 1014: 91.06
+	Hs
		1242674 CNOT2_HUMAN (1-540): 0: 528: 100.00		TNR6A_HUMAN (2-1833): 0: 785: 35.34
+	Hs
		1336203 CNOT2_HUMAN (1-540): 0: 528: 100.00		TNR6C_HUMAN (34-1830): 0: 655: 34.21
+	Hs
		257384 CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19		TNR6A_HUMAN (2-1833): 0: 785: 35.34
+	Hs
		257413 CNOT3_HUMAN (4-524): 3.46e-106: 336: 16.19		TNR6C_HUMAN (34-1830): 0: 655: 34.21
+	Dm
		1249007 RGA_DROME (22-534): 6.07e-96: 305: 29.50		GAWKY_DROME (615-1735): 3.49e-145: 488: 21.36
+	Dm
		1178903 Q7K126_DROME (4-525): 4.7e-76: 258: 15.41		GAWKY_DROME (615-1735): 3.49e-145: 488: 21.36
+	Dm
		113976 M9PB30_DROME (37-438): 2.6e-11: 69: 13.35		M9PB30_DROME (29-1232): 4.2e-118: 420: 9.82