HitPredict

Interactor 1: MARK1 (Q9P0L2)
Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)
Gene: MARK1

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030425 - dendrite
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 795 Hs			1 859
+	Hs
		1349677 MARK1_HUMAN (1-795): 0: 775: 100.00		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1334282 MARK1_HUMAN (1-795): 0: 775: 100.00		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		1336279 MARK1_HUMAN (1-795): 0: 775: 100.00		AGO4_HUMAN (16-859): 0: 1145: 78.51
+	Hs
		1183144 MARK2_HUMAN (2-795): 0: 668: 63.76		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		647977 MARK3_HUMAN (1-795): 0: 664: 63.86		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		1183145 MARK2_HUMAN (2-795): 0: 668: 63.76		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		647978 MARK3_HUMAN (1-795): 0: 664: 63.86		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1183124 MARK2_HUMAN (2-795): 0: 668: 63.76		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		647963 MARK3_HUMAN (1-795): 0: 664: 63.86		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		1183128 MARK2_HUMAN (2-795): 0: 668: 63.76		AGO4_HUMAN (16-859): 0: 1145: 78.51
+	Hs
		647966 MARK3_HUMAN (1-795): 0: 664: 63.86		AGO4_HUMAN (16-859): 0: 1145: 78.51