HitPredict

Interactor 1: TRI38 (O00635)
E3 ubiquitin-protein ligase TRIM38 (EC 2.3.2.27) (RING finger protein 15) (Tripartite motif-containing protein 38) (Zinc finger protein RoRet)
Gene: TRIM38

Interactor 2: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 193
+	Hs
		584910 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2E1_HUMAN (19-193): 2.75e-82: 244: 100.00
+	Hs
		584923 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		1297370 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2E2_HUMAN (4-193): 2.5e-84: 249: 81.96
+	Hs
		584907 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		584916 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		135040 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2E2_HUMAN (4-193): 2.5e-84: 249: 81.96
+	Hs
		851889 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2E1_HUMAN (19-193): 2.75e-82: 244: 100.00
+	Hs
		1336390 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D4_HUMAN (47-192): 2.38e-81: 239: 63.01
+	Hs
		919870 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		849453 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		1282350 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2E3_HUMAN (3-193): 1.26e-78: 235: 77.49
+	Hs
		584918 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95
+	Hs
		135045 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D4_HUMAN (47-192): 2.38e-81: 239: 63.01
+	Hs
		895921 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		135019 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		135012 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		135036 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2E3_HUMAN (3-193): 1.26e-78: 235: 77.49
+	Hs
		135017 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		895851 TRI58_HUMAN (1-464): 5.62e-145: 425: 39.23		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		896547 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95