HitPredict

Interactor 1: STK26 (Q9P289)
Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)
Gene: STK26

Interactor 2: CAB39 (Q9Y376)
Calcium-binding protein 39 (MO25alpha) (Protein Mo25)
Gene: CAB39

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.853

Property	Details
Experiments	23434407, 21423148
Identification Methods	molecular sieving, bio-layer interferometry, anti tag coimmunoprecipitation, x-ray crystallography, comigration in sds page, surface plasmon resonance
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Mo25~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035556 - intracellular signal transduction GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 341
+	Mm
		986131 STK26_MOUSE (1-416): 4.89e-156: 448: 98.08		CAB39_MOUSE (1-341): 0: 511: 99.12
+	Hs
		1377539 STK24_HUMAN (17-411): 1.47e-137: 402: 70.69		CAB39_HUMAN (1-341): 0: 511: 100.00
+	Hs
		131624 STK25_HUMAN (14-411): 7.15e-134: 392: 68.63		CAB39_HUMAN (1-341): 0: 511: 100.00
+	Sp
		144227 PPK11_SCHPO (21-331): 4.43e-124: 363: 47.79		PMO25_SCHPO (1-333): 1.72e-152: 433: 50.15
+	Sp
		252679 NAK1_SCHPO (13-331): 3.13e-87: 280: 45.81		PMO25_SCHPO (1-333): 1.72e-152: 433: 50.15
+	Sc
		690416 KIC1_YEAST (12-316): 4e-77: 260: 45.43		HYM1_YEAST (1-335): 2.14e-141: 407: 33.91