HitPredict

Interactor 1: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Interactor 2: WASF2 (Q9Y6W5)
Actin-binding protein WASF2 (Protein WAVE-2) (Verprolin homology domain-containing protein 2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2)
Gene: WASF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	17101133
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017124 - SH3 domain binding GO:0030027 - lamellipodium GO:0030036 - actin cytoskeleton organization GO:0031209 - SCAR complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 Hs			1 498
+	Hs
		1267036 ABI3_HUMAN (1-366): 1.12e-87: 270: 100.00		WASF1_HUMAN (1-496): 3.22e-43: 162: 43.19
+	Rn
		1124757 ABI1_RAT (1-314): 2.45e-66: 219: 34.88		WASF1_RAT (1-496): 1.76e-41: 157: 43.19
+	Hs
		1052366 SRC8_HUMAN (40-363): 2.07e-42: 157: 16.12		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Hs
		1348444 ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Mm
		1206472 ABI1_MOUSE (272-363): 1.7e-21: 97.4: 44.57		WASF2_MOUSE (1-498): 1.27e-67: 227: 81.73
+	Hs
		203262 PACN2_HUMAN (17-363): 1.11e-44: 162: 14.29		SYNJ1_HUMAN (36-496): 2.09e-41: 161: 13.30
+	Hs
		203224 MYO1E_HUMAN (34-363): 1.97e-42: 159: 18.34		SYNJ1_HUMAN (36-496): 2.09e-41: 161: 13.30
+	Hs
		1224667 ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Hs
		1348432 ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18		WASF3_HUMAN (1-498): 4.08e-58: 202: 46.92
+	Hs
		203251 PACN1_HUMAN (11-363): 5.47e-37: 140: 12.67		SYNJ1_HUMAN (36-496): 2.09e-41: 161: 13.30
+	Hs
		1224659 ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49		WASF3_HUMAN (1-498): 4.08e-58: 202: 46.92
+	Dm
		94643 DBNL_DROME (17-363): 3.62e-33: 131: 15.05		F2FB81_DROME (1-245): 9.78e-42: 160: 41.53
+	Hs
		1021688 MYO1E_HUMAN (34-363): 1.97e-42: 159: 18.34		CBP_HUMAN (38-468): 2.79e-27: 118: 12.79
+	Hs
		1267032 ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18		WASF1_HUMAN (1-496): 3.22e-43: 162: 43.19
+	Hs
		203249 SH3G2_HUMAN (265-363): 7.89e-26: 108: 23.76		SYNJ1_HUMAN (36-496): 2.09e-41: 161: 13.30
+	Hs
		1224624 ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49		WASF1_HUMAN (1-496): 3.22e-43: 162: 43.19
+	Dd
		1122140 ABIA_DICDI (3-321): 6.97e-30: 119: 19.32		SCAR_DICDI (25-478): 2.95e-34: 135: 23.20
+	Rn
		192354 SH3G2_RAT (265-363): 2.5e-26: 109: 23.76		SYNJ1_RAT (41-497): 1.63e-11: 69: 12.89
+	Mm
		88459 SH3G2_MOUSE (265-363): 3.47e-27: 111: 24.75		D3Z656_MOUSE (41-453): 4.33e-10: 64.7: 12.61
+	Ce
		70017 SH3GH_CAEEL (233-363): 6.74e-23: 100: 20.00		G5EBN5_CAEEL (207-437): 8.21e-10: 63.8: 18.03