Interactor 1: TRI38 (O00635)
E3 ubiquitin-protein ligase TRIM38 (EC 2.3.2.27) (RING finger protein 15) (Tripartite motif-containing protein 38) (Zinc finger protein RoRet)
Gene: TRIM38
Interactor 2: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.42 | 0.60 | 0.506 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11854271 |
Identification Methods | coimmunoprecipitation, two hybrid |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005829 - cytosol GO:0042803 - protein homodimerization activity GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0051092 - positive regulation of NF-kappaB transcription factor activity |
Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024