Interactor 1: CPSF2 (Q9P2I0)
Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)
Gene: CPSF2

Interactor 2: CPSF3 (Q9UKF6)
Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73)
Gene: CPSF3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 26496610, 24981860, 18688255, 33961781, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Beta-Casp~Beta-Casp, Beta-Casp~Lactamase_B_6, Beta-Casp~RMMBL, CPSF73-100_C~Lactamase_B_6, Lactamase_B_6~Lactamase_B_6, Lactamase_B_6~RMMBL, RMMBL~RMMBL
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
GO:0006398 - mRNA 3'-end processing by stem-loop binding and cleavage
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 782
Hs

1 684
+ Dm
+ At
+ Sp
+ Zm
+ At
+ At
+ Sp
+ At
+ Sc
+ At
+ At
+ Hs
+ Dm
+ Sc

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Last updated: 15 Jul 2024