HitPredict

Interactor 1: KLHL9 (Q9P2J3)
Kelch-like protein 9
Gene: KLHL9

Interactor 2: UBP25 (Q9UHP3)
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25)
Gene: USP25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	33961781, 28619731, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 617 Hs			1 1055
+	Hs
		307207 KLHL2_HUMAN (29-596): 2.21e-151: 450: 28.10		UBP28_HUMAN (1-1047): 0: 894: 48.57
+	Hs
		1350482 KLH13_HUMAN (448-615): 3.91e-30: 127: 20.59		UBP25_HUMAN (1-1055): 0: 1021: 100.00
+	Hs
		1120797 KLH12_HUMAN (532-615): 1.52e-11: 69.1: 17.86		USP9X_HUMAN (142-459): 2.23e-67: 250: 20.22
+	Hs
		1049236 KEAP1_HUMAN (397-615): 2.34e-54: 197: 28.25		U17L2_HUMAN (563-780): 2.01e-19: 95.4: 18.42
+	Hs
		1049290 KEAP1_HUMAN (397-615): 2.34e-54: 197: 28.25		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78
+	Hs
		64225 KLH20_HUMAN (430-615): 7e-43: 165: 22.46		UBP27_HUMAN (477-674): 2.11e-20: 97.3: 16.16
+	Hs
		1273939 KLHL8_HUMAN (446-615): 1.79e-35: 143: 20.47		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78
+	Hs
		1273805 KLHL5_HUMAN (474-615): 2.82e-28: 122: 22.54		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78