HitPredict

Interactor 1: HECW2 (Q9P2P5)
E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2)
Gene: HECW2

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24163370
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1572 Hs			1 1186
+	Hs
		1199210 HECW2_HUMAN (1-1572): 0: 1176: 100.00		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		1271460 HECW2_HUMAN (1-1572): 0: 1176: 100.00		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		164478 WWP1_HUMAN (614-936): 3.01e-14: 80.2: 16.36		TRI66_HUMAN (20-302): 1.21e-49: 194: 19.60
+	Hs
		164449 ITCH_HUMAN (468-850): 1.52e-10: 68.3: 12.37		TRI66_HUMAN (20-302): 1.21e-49: 194: 19.60
+	Hs
		254006 WWP1_HUMAN (614-936): 3.01e-14: 80.2: 16.36		MTG16_HUMAN (948-1103): 2.32e-42: 167: 24.85
+	Hs
		808275 NEDD4_HUMAN (262-640): 1.79e-13: 77.9: 10.41		SP14L_HUMAN (54-257): 1.55e-39: 157: 18.87
+	Sc
		765374 RSP5_YEAST (572-850): 1.92e-11: 71: 16.10		GCN5_YEAST (120-252): 1.1e-33: 137: 23.88