HitPredict

Interactor 1: HECW2 (Q9P2P5)
E3 ubiquitin-protein ligase HECW2 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECW2) (NEDD4-like E3 ubiquitin-protein ligase 2)
Gene: HECW2

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27498087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1572 Hs			1 779
+	Hs
		1119083 HECW2_HUMAN (1-1572): 0: 1176: 100.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1222275 HECW2_HUMAN (1-1572): 0: 1176: 100.00		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		724896 HUWE1_HUMAN (1007-1571): 2.14e-157: 535: 31.55		MYH9_HUMAN (16-773): 4.81e-28: 123: 9.57
+	Hs
		125503 WWP2_HUMAN (523-857): 7e-16: 85.6: 13.18		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		125805 WWP2_HUMAN (523-857): 7e-16: 85.6: 13.18		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1119034 NED4L_HUMAN (664-1033): 5.09e-15: 82.9: 15.47		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1119052 WWP1_HUMAN (614-936): 3.01e-14: 80.2: 16.36		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1327936 WWP1_HUMAN (614-936): 3.01e-14: 80.2: 16.36		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		808151 NEDD4_HUMAN (262-640): 1.79e-13: 77.9: 10.41		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		808328 NEDD4_HUMAN (262-640): 1.79e-13: 77.9: 10.41		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1119026 ITCH_HUMAN (468-850): 1.52e-10: 68.3: 12.37		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		125569 WWP2_HUMAN (523-857): 7e-16: 85.6: 13.18		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1222263 NED4L_HUMAN (664-1033): 5.09e-15: 82.9: 15.47		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1222267 WWP1_HUMAN (614-936): 3.01e-14: 80.2: 16.36		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		808183 NEDD4_HUMAN (262-640): 1.79e-13: 77.9: 10.41		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1078893 ITCH_HUMAN (468-850): 1.52e-10: 68.3: 12.37		ITSN1_HUMAN (136-766): 1.5e-36: 150: 11.46
+	Hs
		551845 SMUF1_HUMAN (177-586): 4.19e-31: 134: 13.74		DESP_HUMAN (16-454): 7.49e-11: 68.1: 12.02