HitPredict

Interactor 1: NFIB (O00712)
Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein)
Gene: NFIB

Interactor 2: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1902894 - negative regulation of miRNA transcription
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 2440
+	Hs
		261511 NFIX_HUMAN (2-414): 0: 614: 61.70		NCOR1_HUMAN (1-2440): 0: 780: 100.00
+	Hs
		261377 NFIC_HUMAN (1-412): 0: 603: 64.86		NCOR1_HUMAN (1-2440): 0: 780: 100.00
+	Hs
		261488 NFIA_HUMAN (2-414): 0: 573: 63.12		NCOR1_HUMAN (1-2440): 0: 780: 100.00
+	Hs
		135181 NFIB_HUMAN (1-420): 0: 702: 100.00		NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71
+	Hs
		1060396 NFIX_HUMAN (2-414): 0: 614: 61.70		NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71
+	Hs
		443276 NFIC_HUMAN (1-412): 0: 603: 64.86		NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71
+	Hs
		1018287 NFIA_HUMAN (2-414): 0: 573: 63.12		NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71
+	Hs
		135169 NFIB_HUMAN (1-420): 0: 702: 100.00		RCOR3_HUMAN (417-809): 8.57e-87: 295: 18.92
+	Hs
		135173 NFIB_HUMAN (1-420): 0: 702: 100.00		RCOR1_HUMAN (360-717): 6.64e-75: 260: 19.40
+	Hs
		443261 NFIC_HUMAN (1-412): 0: 603: 64.86		RCOR3_HUMAN (417-809): 8.57e-87: 295: 18.92
+	Hs
		135133 NFIB_HUMAN (1-420): 0: 702: 100.00		KMT2C_HUMAN (1352-2176): 4.42e-47: 190: 15.30
+	Hs
		1060330 NFIX_HUMAN (2-414): 0: 614: 61.70		KMT2C_HUMAN (1352-2176): 4.42e-47: 190: 15.30
+	Hs
		135148 NFIB_HUMAN (1-420): 0: 702: 100.00		CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05
+	Hs
		1060360 NFIX_HUMAN (2-414): 0: 614: 61.70		MINT_HUMAN (468-2394): 3.2e-23: 111: 8.72
+	Hs
		1060314 NFIX_HUMAN (2-414): 0: 614: 61.70		SRCAP_HUMAN (1602-2436): 2.94e-20: 101: 10.64
+	Hs
		1060359 NFIX_HUMAN (2-414): 0: 614: 61.70		CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05
+	Hs
		443234 NFIC_HUMAN (1-412): 0: 603: 64.86		CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05
+	Hs
		1018255 NFIA_HUMAN (2-414): 0: 573: 63.12		CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05