Interactor 1: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 21628003, 16670331, 14966134, 19451267
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, TIR~TIR
Common GO terms GO:0001530 - lipopolysaccharide binding
GO:0001726 - ruffle
GO:0001774 - microglial cell activation
GO:0001875 - lipopolysaccharide immune receptor activity
GO:0001891 - phagocytic cup
and 113 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 835
Mm

1 835
+ Mm
+ At
+ Hs
+ At
+ Mm
+ At
+ Hs
+ At
+ At
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024