Interactor 1: UCHL1 (Q9R0P9)
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Gene: UCHL1

Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 25403879
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C12~ubiquitin
Common GO terms GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0030424 - axon
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 223
Mm

1 464
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ Mm
+ Mm
+ Rn
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024