HitPredict

Interactor 1: CLPB (Q9RA63)
Chaperone protein ClpB
Gene: CLPB

Interactor 2: CLPB (Q9RA63)
Chaperone protein ClpB
Gene: CLPB

Species: Thermus thermophilus HB8

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.902

Property	Details
Experiments	22802670, 14567920, 22348341, 21554542
Identification Methods	x-ray crystallography, cross-linking study, molecular sieving
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	AAA~AAA, AAA~AAA_2, AAA~AAA_lid_9, AAA~Clp_N, AAA~ClpB_D2-small, AAA_2~AAA_2, AAA_2~AAA_lid_9, AAA_2~ClpB_D2-small, AAA_lid_9~AAA_lid_9, AAA_lid_9~Clp_N, AAA_lid_9~ClpB_D2-small, Clp_N~Clp_N, ClpB_D2-small~ClpB_D2-small
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity GO:0034605 - cellular response to heat GO:0042026 - protein refolding and 1 others more... GO:0043335 - protein unfolding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 854 Tt			1 854
+	Ec
		930511 CLPB_ECOLI (1-848): 0: 809: 56.53		CLPB_ECOLI (1-848): 0: 809: 56.53
+	Sp
		293888 HS104_SCHPO (1-854): 0: 749: 47.29		HS104_SCHPO (1-854): 0: 749: 47.29
+	Sc
		680504 HS104_YEAST (2-843): 0: 676: 42.91		HS104_YEAST (2-843): 0: 676: 42.91
+	Sc
		680586 HS104_YEAST (2-843): 0: 676: 42.91		HSP78_YEAST (139-850): 0: 658: 53.00
+	Pf
		1212793 Q8IIJ8_PLAF7 (3-849): 0: 641: 36.47		Q8IIJ8_PLAF7 (3-849): 0: 641: 36.47
+	Sc
		681040 HS104_YEAST (2-843): 0: 676: 42.91		RIX7_YEAST (54-475): 1.34e-24: 112: 16.07
+	Sc
		705724 HSP78_YEAST (139-850): 0: 658: 53.00		RIX7_YEAST (54-475): 1.34e-24: 112: 16.07
+	Cj
		1007187 Q0P9E6_CAMJE (380-844): 1.54e-67: 240: 29.89		Q0P9E6_CAMJE (380-844): 1.54e-67: 240: 29.89
+	Sp
		145403 YB7A_SCHPO (404-811): 1.1e-36: 150: 13.00		YB7A_SCHPO (404-811): 1.1e-36: 150: 13.00
+	Sc
		992244 RIX7_YEAST (54-475): 1.34e-24: 112: 16.07		RIX7_YEAST (54-475): 1.34e-24: 112: 16.07