HitPredict

Interactor 1: RUB1 (Q9SHE7)
Ubiquitin-NEDD8-like protein RUB1 [Cleaved into: Ubiquitin; NEDD8-like protein RUB1 (Ubiquitin-related protein 1) (AtRUB1)]
Gene: RUB1

Interactor 2: CUL3A (Q9ZVH4)
Cullin-3A (AtCUL3a)
Gene: CUL3A

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15618422
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cullin~ubiquitin, Cullin_Nedd8~ubiquitin
Common GO terms	GO:0016567 - protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 At			1 732
+	At
		1321116 RUB1_ARATH (1-156): 1.66e-61: 188: 100.00		CUL3B_ARATH (1-732): 0: 919: 88.12
+	Hs
		475728 UBC_HUMAN (1-152): 5.68e-58: 193: 78.95		CUL3_HUMAN (3-732): 0: 846: 51.64
+	Hs
		475729 UBC_HUMAN (1-152): 5.68e-58: 193: 78.95		CUL4A_HUMAN (6-732): 0: 812: 38.75
+	Hs
		475730 UBC_HUMAN (1-152): 5.68e-58: 193: 78.95		CUL4B_HUMAN (4-732): 0: 802: 39.05
+	Rn
		78188 UBC_RAT (1-105): 3.61e-31: 119: 80.95		CUL3_RAT (3-732): 0: 845: 51.51
+	Mm
		477034 UBC_MOUSE (1-105): 2.61e-31: 119: 82.86		CUL3_MOUSE (3-732): 0: 844: 51.38
+	Hs
		923983 RS27A_HUMAN (77-152): 8.46e-29: 105: 61.84		CUL3_HUMAN (3-732): 0: 846: 51.64
+	Hs
		475726 UBC_HUMAN (1-152): 5.68e-58: 193: 78.95		CUL1_HUMAN (25-732): 0: 747: 30.47
+	At
		1091919 UBQ3_ARATH (1-152): 2.92e-60: 190: 80.92		CUL1_ARATH (25-732): 0: 736: 33.78
+	At
		1277343 RUB1_ARATH (1-156): 1.66e-61: 188: 100.00		CUL1_ARATH (25-732): 0: 736: 33.78
+	Rn
		71349 UBC_RAT (1-105): 3.61e-31: 119: 80.95		B2RYJ3_RAT (3-732): 0: 804: 38.72
+	Hs
		923984 RS27A_HUMAN (77-152): 8.46e-29: 105: 61.84		CUL4A_HUMAN (6-732): 0: 812: 38.75
+	Hs
		923985 RS27A_HUMAN (77-152): 8.46e-29: 105: 61.84		CUL4B_HUMAN (4-732): 0: 802: 39.05
+	Hs
		475727 UBC_HUMAN (1-152): 5.68e-58: 193: 78.95		CUL2_HUMAN (25-732): 0: 708: 30.21
+	Sp
		142914 UBI4P_SCHPO (1-152): 2.59e-58: 187: 79.61		CUL1_SCHPO (28-732): 0: 686: 29.99
+	Rn
		70071 UBC_RAT (1-105): 3.61e-31: 119: 80.95		B1WBY1_RAT (25-732): 0: 747: 30.47
+	Mm
		477001 UBC_MOUSE (1-105): 2.61e-31: 119: 82.86		CUL2_MOUSE (25-732): 0: 706: 30.08
+	Hs
		476148 UBC_HUMAN (1-152): 5.68e-58: 193: 78.95		CUL5_HUMAN (25-732): 0: 581: 23.36
+	Rn
		1144279 UBC_RAT (1-105): 3.61e-31: 119: 80.95		CUL5_RAT (25-732): 0: 583: 22.97
+	Mm
		477002 UBC_MOUSE (1-105): 2.61e-31: 119: 82.86		CUL5_MOUSE (25-732): 0: 580: 22.97