HitPredict

Interactor 1: VPS2A (Q9SKI2)
Vacuolar protein sorting-associated protein 2 homolog 1 (AtVPS2-1) (Charged multivesicular body protein 2 homolog 1) (ESCRT-III complex subunit VPS2 homolog 1) (SNF7-like protein)
Gene: VPS2.1

Interactor 2: VPS4 (Q9ZNT0)
Protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1 (AtSKD1) (EC 3.6.4.6) (Protein VACUOLAR PROTEIN SORTING 4)
Gene: SKD1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21810997
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005771 - multivesicular body GO:0015031 - protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 225 At			1 435
+	At
		1013169 VPS2B_ARATH (4-225): 2.41e-50: 164: 40.54		VPS4_ARATH (1-435): 1.73e-129: 382: 100.00
+	At
		1352776 CHM1B_ARATH (14-223): 4.5e-40: 137: 21.91		VPS4_ARATH (1-435): 1.73e-129: 382: 100.00
+	Hs
		208869 CHM2A_HUMAN (2-224): 3.76e-48: 159: 54.26		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Hs
		1357379 CHMP3_HUMAN (5-223): 2.55e-47: 157: 25.34		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Sc
		732854 DID4_YEAST (1-224): 1.61e-53: 173: 43.86		VPS4_YEAST (2-435): 1.23e-113: 342: 53.30
+	Hs
		208804 CHM2A_HUMAN (2-224): 3.76e-48: 159: 54.26		VPS4B_HUMAN (2-435): 1.76e-117: 352: 53.02
+	Hs
		1357378 CHM2B_HUMAN (8-206): 2.43e-45: 151: 37.19		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Mm
		804060 CHM2A_MOUSE (2-224): 5.35e-49: 161: 54.71		VPS4B_MOUSE (2-435): 6.18e-116: 348: 52.80
+	Hs
		260164 CHM2B_HUMAN (8-206): 2.43e-45: 151: 37.19		VPS4B_HUMAN (2-435): 1.76e-117: 352: 53.02
+	Dm
		1373132 Q9VRJ5_DROME (1-201): 3.37e-48: 159: 34.83		Q9Y162_DROME (5-435): 1.87e-111: 336: 52.48
+	Dm
		1362012 Q9VBI3_DROME (2-202): 1.64e-47: 158: 52.24		Q9Y162_DROME (5-435): 1.87e-111: 336: 52.48
+	Dm
		1371193 Q9VN02_DROME (8-223): 8.28e-47: 156: 23.61		Q9Y162_DROME (5-435): 1.87e-111: 336: 52.48
+	Hs
		1336687 CHM1A_HUMAN (21-224): 1.77e-37: 131: 22.55		VPS4A_HUMAN (1-434): 6.16e-120: 358: 52.13
+	Hs
		260156 CHM1A_HUMAN (21-224): 1.77e-37: 131: 22.55		VPS4B_HUMAN (2-435): 1.76e-117: 352: 53.02
+	Sc
		732543 VPS24_YEAST (10-224): 3.66e-41: 141: 22.22		VPS4_YEAST (2-435): 1.23e-113: 342: 53.30
+	Hs
		260145 CHM1B_HUMAN (16-223): 1.44e-35: 126: 24.04		VPS4B_HUMAN (2-435): 1.76e-117: 352: 53.02
+	Dm
		1248702 Q8SXB1_DROME (15-202): 7.11e-40: 138: 52.66		Q9Y162_DROME (5-435): 1.87e-111: 336: 52.48
+	Dm
		1279493 Q95SH2_DROME (16-224): 2.28e-38: 133: 23.92		Q9Y162_DROME (5-435): 1.87e-111: 336: 52.48
+	Hs
		208865 CHM2A_HUMAN (2-224): 3.76e-48: 159: 54.26		SPAST_HUMAN (77-355): 1.12e-62: 214: 44.06
+	Hs
		1185555 CHM1B_HUMAN (16-223): 1.44e-35: 126: 24.04		SPAST_HUMAN (77-355): 1.12e-62: 214: 44.06