HitPredict

Interactor 1: CRF4 (Q9SUE3)
Ethylene-responsive transcription factor CRF4 (Protein CYTOKININ RESPONSE FACTOR 4)
Gene: CRF4

Interactor 2: CRF2 (Q9SUQ2)
Ethylene-responsive transcription factor CRF2 (Protein CYTOKININ RESPONSE FACTOR 2)
Gene: CRF2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.723

Property	Details
Experiments	21705390
Identification Methods	protein complementation assay, two hybrid, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	AP2~AP2
Common GO terms	GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0009736 - cytokinin-activated signaling pathway GO:0009873 - ethylene-activated signaling pathway
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 335 At			1 343
+	At
		1323870 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		CRF2_ARATH (1-343): 1.03e-108: 322: 100.00
+	At
		1323869 CRF4_ARATH (1-335): 7.5e-93: 281: 100.00		CRF3_ARATH (3-342): 3.37e-68: 219: 31.58
+	At
		1352861 CRF4_ARATH (1-335): 7.5e-93: 281: 100.00		CRF4_ARATH (1-342): 2.86e-67: 216: 34.92
+	At
		287640 CRF4_ARATH (1-335): 7.5e-93: 281: 100.00		CRF1_ARATH (32-343): 7.66e-64: 206: 50.95
+	At
		287517 CRF4_ARATH (1-335): 7.5e-93: 281: 100.00		CRF5_ARATH (9-330): 3.39e-59: 194: 33.43
+	At
		1341158 CRF4_ARATH (1-335): 7.5e-93: 281: 100.00		CRF6_ARATH (10-295): 1.77e-52: 177: 32.99
+	At
		1323855 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		CRF3_ARATH (3-342): 3.37e-68: 219: 31.58
+	At
		1320973 CRF4_ARATH (1-335): 7.5e-93: 281: 100.00		ERF70_ARATH (34-199): 7.39e-46: 155: 42.11
+	At
		287632 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		CRF1_ARATH (32-343): 7.66e-64: 206: 50.95
+	At
		287513 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		CRF5_ARATH (9-330): 3.39e-59: 194: 33.43
+	At
		287641 CRF2_ARATH (1-334): 2.99e-64: 208: 31.09		CRF1_ARATH (32-343): 7.66e-64: 206: 50.95
+	At
		1259026 CRF4_ARATH (1-335): 7.5e-93: 281: 100.00		ERF69_ARATH (34-201): 5.81e-37: 132: 42.11
+	At
		1323865 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		CRF6_ARATH (10-295): 1.77e-52: 177: 32.99
+	At
		287518 CRF2_ARATH (1-334): 2.99e-64: 208: 31.09		CRF5_ARATH (9-330): 3.39e-59: 194: 33.43
+	At
		1320966 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		ERF70_ARATH (34-199): 7.39e-46: 155: 42.11
+	At
		1323863 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		EF119_ARATH (28-298): 6.48e-39: 142: 22.94
+	At
		1320974 CRF2_ARATH (1-334): 2.99e-64: 208: 31.09		ERF70_ARATH (34-199): 7.39e-46: 155: 42.11
+	At
		1259021 CRF3_ARATH (3-334): 1.62e-72: 230: 50.42		ERF69_ARATH (34-201): 5.81e-37: 132: 42.11
+	At
		1259027 CRF2_ARATH (1-334): 2.99e-64: 208: 31.09		ERF69_ARATH (34-201): 5.81e-37: 132: 42.11