Interactor 1: SPT4H (Q9TVQ5)
Transcription elongation factor SPT4 (DRB sensitivity-inducing factor small subunit) (DSIF small subunit) (dSpt4)
Gene: spt4

Interactor 2: SPT5H (Q9V460)
Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (dSpt5)
Gene: Spt5

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 23894613, 28213523, 29208012, 25242320, 20534440
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains KOW~Spt4, Spt4~Spt5-NGN
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000993 - RNA polymerase II complex binding
GO:0005703 - polytene chromosome puff
GO:0005705 - polytene chromosome interband
GO:0006368 - transcription elongation by RNA polymerase II
and 7 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 116
Dm

1 1078
+ Mm
+ Hs
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024