HitPredict

Interactor 1: Q9U2T9 (Q9U2T9)
Intersectin-1
Gene: itsn-1

Interactor 2: NUMB1 (Q9XTY6)
Numb-related protein 1 (CKA1) (Protein kinase C adapter 1)
Gene: num-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.595

Property	Details
Experiments	18298590, 23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1085 Ce			1 593
+	Ce
		60780 Q9U2T9_CAEEL (1-1085): 6.1e-161: 506: 100.00		A5JYR4_CAEEL (65-481): 6.22e-50: 181: 15.58
+	Ce
		283754 Q9U2T9_CAEEL (1-1085): 6.1e-161: 506: 100.00		CED6_CAEEL (73-326): 7.89e-45: 167: 15.63
+	Ce
		1274646 Q9U2T9_CAEEL (1-1085): 6.1e-161: 506: 100.00		Q93203_CAEEL (54-234): 2.22e-15: 82: 17.46
+	Hs
		833668 EP15R_HUMAN (5-473): 6.97e-71: 256: 22.69		NUMB_HUMAN (59-583): 3.44e-82: 272: 28.60
+	Hs
		787868 EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12		NUMB_HUMAN (59-583): 3.44e-82: 272: 28.60
+	Mm
		788008 EPS15_MOUSE (4-464): 1.55e-54: 208: 20.78		NUMB_MOUSE (59-583): 1.03e-84: 279: 28.55
+	Dm
		91154 E3CTP7_DROME (5-492): 4.03e-56: 211: 19.41		NUMB_DROME (47-584): 3.11e-65: 225: 31.04
+	Hs
		787894 EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12		DAB2_HUMAN (59-586): 7.48e-46: 174: 13.05
+	Mm
		1141842 EP15R_MOUSE (5-477): 2.19e-56: 213: 21.52		ANS1B_MOUSE (60-269): 9.01e-50: 188: 19.91
+	Mm
		957141 EP15R_MOUSE (5-477): 2.19e-56: 213: 21.52		DAB2_MOUSE (59-586): 1.3e-46: 177: 13.83
+	Mm
		787999 EPS15_MOUSE (4-464): 1.55e-54: 208: 20.78		DAB2_MOUSE (59-586): 1.3e-46: 177: 13.83
+	Hs
		269120 NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27		DAB1_HUMAN (63-578): 4.23e-56: 201: 14.52
+	Mm
		223010 NCK2_MOUSE (660-958): 2.72e-26: 114: 19.47		DAB1_MOUSE (63-562): 9.56e-58: 205: 14.79
+	Hs
		557659 NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27		DAB2_HUMAN (59-586): 7.48e-46: 174: 13.05
+	Hs
		208964 NCK2_HUMAN (660-960): 3.34e-25: 110: 18.69		DAB1_HUMAN (63-578): 4.23e-56: 201: 14.52
+	Hs
		209098 NCK2_HUMAN (660-960): 3.34e-25: 110: 18.69		ANS1B_HUMAN (60-259): 1.86e-50: 190: 19.43
+	Hs
		269148 ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35		DAB1_HUMAN (63-578): 4.23e-56: 201: 14.52
+	Ce
		283748 YKA7_CAEEL (665-936): 1.1e-19: 95.9: 16.61		CED6_CAEEL (73-326): 7.89e-45: 167: 15.63
+	Hs
		666186 VAV3_HUMAN (875-1084): 4.84e-15: 82.1: 18.11		SHC1_HUMAN (39-420): 4.95e-47: 175: 12.65
+	Hs
		957186 ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35		DAB2_HUMAN (59-586): 7.48e-46: 174: 13.05