Interactor 1: DNM3B (Q9UBC3)
DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB)
Gene: DNMT3B

Interactor 2: DNM3L (Q9UJW3)
DNA (cytosine-5)-methyltransferase 3-like
Gene: DNMT3L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 24952347, 15105426, 11934864, 17687327, 12777184
Identification Methods pull down, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ADD_DNMT3~ADD_DNMT3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0032259 - methylation
GO:0046872 - metal ion binding
and 2 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 853
Hs

1 386
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm

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Last updated: 15 Jul 2024