HitPredict

Interactor 1: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35676659
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1215 Hs			1 447
+	Hs
		929705 HDAC6_HUMAN (1-1215): 0: 1435: 100.00		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Hs
		1038686 HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09		TBL1R_HUMAN (3-260): 1.52e-55: 193: 11.40
+	Hs
		1270423 HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02		TBL1R_HUMAN (3-260): 1.52e-55: 193: 11.40
+	Hs
		245600 HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Hs
		880817 HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51		TBL1R_HUMAN (3-260): 1.52e-55: 193: 11.40
+	Hs
		1260185 HDAC7_HUMAN (440-891): 6.38e-147: 469: 36.44		TBL1R_HUMAN (3-260): 1.52e-55: 193: 11.40
+	Hs
		1318188 HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48		TBL1R_HUMAN (3-260): 1.52e-55: 193: 11.40
+	Hs
		245623 HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Hs
		177377 HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29		TBL1R_HUMAN (3-260): 1.52e-55: 193: 11.40
+	Hs
		245584 HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Hs
		245622 HDAC7_HUMAN (440-891): 6.38e-147: 469: 36.44		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Hs
		245649 HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Hs
		903202 HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		177148 HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Hs
		1270370 HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02		SNR40_HUMAN (258-447): 3.49e-34: 132: 13.02
+	Hs
		903404 HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		903610 HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		177249 HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		282986 HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02		CIAO1_HUMAN (81-215): 3.8e-16: 81.1: 18.12
+	Dm
		1212080 Q8I9J6_DROME (434-889): 6.81e-145: 471: 33.33		EBI_DROME (358-443): 2.35e-11: 67.9: 10.20