Interactor 1: EIF3K (Q9UBQ5)
Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28)
Gene: EIF3K

Interactor 2: EIF3L (Q9Y262)
Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein)
Gene: EIF3L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 25416956, 16189514, 21516116, 35271311, 28514442, 32296183, 24981860, 33961781, 19748344, 18599441, 23623729, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, mass spectrometry studies of complexes, pull down, anti tag coimmunoprecipitation, validated two hybrid, two hybrid pooling approach, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN8_PSD8_EIF3K~Paf67
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005852 - eukaryotic translation initiation factor 3 complex
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 218
Hs

1 564
+ Dm
+ Ce

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Last updated: 15 Jul 2024