HitPredict

Interactor 1: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25324306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 303
+	Hs
		682070 AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Mm
		682131 AKT1_MOUSE (5-391): 1.98e-153: 447: 39.44		CHIP_MOUSE (1-303): 1.23e-67: 214: 97.37
+	Hs
		568829 KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		616689 KS6B1_HUMAN (1-476): 3.36e-173: 499: 68.58		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Rn
		858690 AKT3_RAT (6-391): 7.74e-152: 442: 39.59		PPP5_RAT (1-259): 9.7e-36: 136: 20.91
+	Hs
		117035 SGK1_HUMAN (55-393): 4e-100: 308: 47.03		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00