HitPredict

Interactor 1: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	20098747
Identification Methods	pull down, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 419
+	Mm
		291781 AKT1_MOUSE (5-391): 1.98e-153: 447: 39.44		NEMO_MOUSE (1-419): 3e-53: 184: 86.64
+	Hs
		682095 AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		969123 KPCE_HUMAN (2-395): 2.02e-145: 435: 34.23		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Mm
		291793 KPCT_MOUSE (8-395): 3.15e-145: 433: 34.52		NEMO_MOUSE (1-419): 3e-53: 184: 86.64
+	Hs
		981068 KPCT_HUMAN (8-399): 2.54e-145: 433: 34.67		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		682219 AKT2_HUMAN (26-391): 9.02e-155: 450: 41.24		MYO5A_HUMAN (38-342): 1.7e-24: 108: 14.65
+	Hs
		551616 AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		551672 KPCE_HUMAN (2-395): 2.02e-145: 435: 34.23		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		681696 AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		724784 KPCE_HUMAN (2-395): 2.02e-145: 435: 34.23		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Mm
		554901 KPCE_MOUSE (2-395): 5.27e-145: 434: 33.74		MYH6_MOUSE (3-376): 6.43e-10: 63.4: 14.67
+	Mm
		554927 KPCE_MOUSE (2-395): 5.27e-145: 434: 33.74		MYH7_MOUSE (26-376): 1.8e-09: 61.9: 13.24
+	Dm
		397193 KPC1_DROME (36-395): 8.61e-144: 429: 35.91		MYSN_DROME (48-367): 2.18e-10: 65: 19.89
+	Hs
		117041 SGK1_HUMAN (55-393): 4e-100: 308: 47.03		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		568567 KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		568568 KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09
+	Hs
		270416 KS6A5_HUMAN (2-325): 6.86e-97: 311: 23.32		ITSN1_HUMAN (24-403): 1.07e-30: 127: 12.15
+	Hs
		1071723 KS6A2_HUMAN (5-380): 5.48e-104: 328: 26.46		MRCKB_HUMAN (39-356): 2.85e-10: 64.7: 13.60
+	Hs
		116964 SGK1_HUMAN (55-393): 4e-100: 308: 47.03		MYH1_HUMAN (33-391): 2.48e-10: 65: 11.75