HitPredict

Interactor 1: DJB11 (Q9UBS4)
DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4)
Gene: DNAJB11

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Hs			1 1620
+	Hs
		666658 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		434302 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		445882 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		ROS1_HUMAN (1039-1461): 3.68e-112: 397: 37.75
+	Hs
		169212 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		MUSK_HUMAN (983-1391): 2.02e-118: 396: 29.98
+	Hs
		411515 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435790 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		243261 DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		507875 DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411313 DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		243277 DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		435551 DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		243254 DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		243262 DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		537779 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		INSRR_HUMAN (1082-1384): 2.38e-70: 262: 43.46
+	Hs
		385658 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1081636 DJB11_HUMAN (1-358): 1.83e-141: 407: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		384352 DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		681463 DNJA1_HUMAN (20-356): 3.06e-116: 344: 31.88		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		243251 DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		243425 DNJA2_HUMAN (21-349): 3.9e-113: 336: 34.35		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03