Interactor 1: SAE2 (Q9UBT2)
SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Anthracycline-associated resistance ARX) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2)
Gene: UBA2

Interactor 2: SAE2 (Q9UBT2)
SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Anthracycline-associated resistance ARX) (Ubiquitin-like 1-activating enzyme E1B) (Ubiquitin-like modifier-activating enzyme 2)
Gene: UBA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 28292943, 31575873
Identification Methods pull down, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ThiF~ThiF, ThiF~UAE_UbL
Common GO terms GO:0000287 - magnesium ion binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016740 - transferase activity
and 8 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 640
Hs

1 640
+ Sc
+ Sc
+ Zm
+ Oc
+ Hs
+ Hs
+ Dm
+ Sc
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024