HitPredict

Interactor 1: POLK (Q9UBT6)
DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP)
Gene: POLK

Interactor 2: REV1 (Q9UBZ9)
DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)
Gene: REV1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 26903512, 15189446, 26982350, 22859295, 15380106, 19170759
Identification Methods pull down, two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IMS~IMS, IMS~IMS_C, IMS_C~IMS_C, IMS~IMS_HHH, IMS_C~IMS_HHH
Common GO terms GO:0003684 - damaged DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0042276 - error-prone translesion synthesis
and 1 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 870
Hs

1 1251
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024