HitPredict

Interactor 1: SE1L1 (Q9UBV2)
Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)
Gene: SEL1L

Interactor 2: UB2J1 (Q9Y385)
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Gene: UBE2J1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	22119785, 28827405, 18711132
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0036503 - ERAD pathway
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 794 Hs			1 318
+	Hs
		851825 CTR9_HUMAN (250-739): 2.85e-57: 214: 15.08		UB2E1_HUMAN (1-156): 1.67e-64: 203: 28.30
+	Hs
		829022 CTR9_HUMAN (250-739): 2.85e-57: 214: 15.08		UBE2A_HUMAN (7-154): 3.69e-61: 193: 21.85
+	Hs
		927759 CTR9_HUMAN (250-739): 2.85e-57: 214: 15.08		UBE2B_HUMAN (7-154): 6.08e-60: 190: 22.52
+	Hs
		341431 FA12_HUMAN (104-168): 4.1e-25: 112: 40.91		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		341424 FA12_HUMAN (104-168): 4.1e-25: 112: 40.91		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		341429 FA12_HUMAN (104-168): 4.1e-25: 112: 40.91		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		341425 FA12_HUMAN (104-168): 4.1e-25: 112: 40.91		UB2E1_HUMAN (1-156): 1.67e-64: 203: 28.30