HitPredict

Interactor 1: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Interactor 2: KLH21 (Q9UJP4)
Kelch-like protein 21
Gene: KLHL21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30190310
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 701 Hs			1 597
+	Hs
		1153798 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH10_HUMAN (1-560): 6.34e-150: 446: 23.49
+	Hs
		1350369 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLHL9_HUMAN (12-558): 3.24e-148: 443: 27.18
+	Hs
		1327770 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH25_HUMAN (2-550): 4.39e-143: 428: 30.14
+	Hs
		152501 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		ENC1_HUMAN (12-547): 6.97e-72: 243: 30.67
+	Hs
		1121505 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH26_HUMAN (12-548): 1.9e-58: 207: 29.51
+	Hs
		1049349 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KEAP1_HUMAN (250-597): 6.32e-57: 204: 15.30
+	Hs
		1354637 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLHL3_HUMAN (371-595): 1.1e-55: 199: 23.01
+	Hs
		1348054 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH28_HUMAN (368-595): 9.13e-51: 186: 21.22
+	Hs
		307226 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLHL2_HUMAN (384-595): 3.72e-50: 184: 23.11
+	Hs
		1354642 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH20_HUMAN (452-595): 1.94e-32: 134: 22.52
+	Hs
		1164601 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH17_HUMAN (266-421): 2.56e-24: 109: 27.61
+	Hs
		1350481 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH13_HUMAN (479-595): 2.96e-24: 109: 19.84
+	Hs
		1164633 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH24_HUMAN (436-594): 1.4e-22: 104: 15.39
+	Hs
		1354646 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		IPP_HUMAN (513-597): 2.4e-14: 77.9: 18.48
+	Hs
		1120825 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH12_HUMAN (499-595): 2.13e-13: 74.8: 21.00
+	Hs
		1239687 FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00		KLH23_HUMAN (236-382): 3.67e-10: 64.8: 19.46