HitPredict

Interactor 1: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	23277359, 33853758, 33711283, 35944360, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 708 Hs			1 2610
+	Hs
		1350492 ZRAN1_HUMAN (1-697): 0: 987: 100.00		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		304378 ZRAN1_HUMAN (1-697): 0: 987: 100.00		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		1294881 ZRAN1_HUMAN (1-697): 0: 987: 100.00		ITCH_HUMAN (2234-2608): 3.18e-117: 398: 21.88
+	Hs
		1056639 ZRAN1_HUMAN (1-697): 0: 987: 100.00		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		983263 ZRAN1_HUMAN (1-697): 0: 987: 100.00		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	Hs
		1072729 ZRAN1_HUMAN (1-697): 0: 987: 100.00		UBE3C_HUMAN (2405-2610): 9.09e-23: 109: 32.37
+	Hs
		1223646 ZRAN1_HUMAN (1-697): 0: 987: 100.00		HACE1_HUMAN (204-449): 1.11e-20: 102: 14.96
+	Hs
		125519 OTU7B_HUMAN (322-701): 2.32e-127: 400: 25.54		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Mm
		103610 OTU7A_MOUSE (299-701): 3.22e-123: 391: 25.33		ANK3_MOUSE (8-1037): 1.34e-90: 331: 12.59
+	Hs
		599715 TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		599713 TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74		ITCH_HUMAN (2234-2608): 3.18e-117: 398: 21.88