HitPredict

Interactor 1: GCP4 (Q9UGJ1)
Gamma-tubulin complex component 4 (GCP-4) (hGCP4) (Gamma-ring complex protein 76 kDa) (h76p) (hGrip76)
Gene: TUBGCP4

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	25332235, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 542
+	Hs
		1355107 GCP4_HUMAN (1-667): 0: 663: 100.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1287588 GCP3_HUMAN (1-662): 2.3e-169: 509: 16.78		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1311292 GCP2_HUMAN (1-664): 2.74e-169: 508: 18.06		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1287593 GCP3_HUMAN (1-662): 2.3e-169: 509: 16.78		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1311294 GCP2_HUMAN (1-664): 2.74e-169: 508: 18.06		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1301506 GCP5_HUMAN (1-649): 1.21e-132: 417: 15.64		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1301508 GCP5_HUMAN (1-649): 1.21e-132: 417: 15.64		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1301492 GCP6_HUMAN (1-408): 7.41e-75: 264: 13.26		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1301493 GCP6_HUMAN (1-408): 7.41e-75: 264: 13.26		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		197081 GCP2_HUMAN (1-664): 2.74e-169: 508: 18.06		PRP4_HUMAN (320-536): 4.83e-42: 159: 22.13