HitPredict

Interactor 1: SWP70 (Q9UH65)
Switch-associated protein 70 (SWAP-70)
Gene: SWAP70

Interactor 2: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 585 Hs			1 486
+	Hs
		1078931 ITSN1_HUMAN (174-585): 6.34e-40: 158: 14.12		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		1329256 TARA_HUMAN (261-583): 9.46e-11: 67.2: 13.89		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		147146 EPS15_HUMAN (175-576): 8.99e-48: 181: 16.14		FCHO1_HUMAN (14-442): 2.59e-46: 174: 13.33
+	Hs
		787902 EPS15_HUMAN (175-576): 8.99e-48: 181: 16.14		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		147162 ITSN1_HUMAN (174-585): 6.34e-40: 158: 14.12		FCHO1_HUMAN (14-442): 2.59e-46: 174: 13.33
+	Hs
		1315994 TARA_HUMAN (261-583): 9.46e-11: 67.2: 13.89		PACN1_HUMAN (1-485): 3.17e-82: 263: 61.73
+	Hs
		1001577 ITSN1_HUMAN (174-585): 6.34e-40: 158: 14.12		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		1078897 ITSN1_HUMAN (174-585): 6.34e-40: 158: 14.12		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		1329254 TARA_HUMAN (261-583): 9.46e-11: 67.2: 13.89		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		725061 MYH9_HUMAN (237-570): 5.41e-09: 61.4: 13.65		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		147194 EP15R_HUMAN (431-585): 1.02e-13: 76.4: 12.26		FCHO1_HUMAN (14-442): 2.59e-46: 174: 13.33
+	Hs
		1001598 EP15R_HUMAN (431-585): 1.02e-13: 76.4: 12.26		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		724794 MYH9_HUMAN (237-570): 5.41e-09: 61.4: 13.65		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		297971 ITSN1_HUMAN (174-585): 6.34e-40: 158: 14.12		FCSD2_HUMAN (38-485): 6.87e-12: 69.8: 13.81
+	Hs
		1021686 MY18A_HUMAN (271-584): 1.56e-10: 66.4: 14.61		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		1052202 PLEC_HUMAN (316-521): 1.19e-10: 67.1: 22.28		SRC8_HUMAN (47-484): 5.84e-38: 147: 11.40
+	Hs
		148746 CTRO_HUMAN (234-585): 7.53e-10: 64.5: 10.35		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		1052276 MY18A_HUMAN (271-584): 1.56e-10: 66.4: 14.61		SRC8_HUMAN (47-484): 5.84e-38: 147: 11.40
+	Hs
		724801 MYH9_HUMAN (237-570): 5.41e-09: 61.4: 13.65		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		724825 MYH9_HUMAN (237-570): 5.41e-09: 61.4: 13.65		SRC8_HUMAN (47-484): 5.84e-38: 147: 11.40