Interactor 1: WN10B (O00744)
Protein Wnt-10b (Protein Wnt-12)
Gene: WNT10B

Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005576 - extracellular region
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 389
Hs

1 2471
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Last updated: 15 Jul 2024