HitPredict

Interactor 1: DDX20 (Q9UHI6)
Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3)
Gene: DDX20

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	29395067, 10601333
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000244 - spliceosomal tri-snRNP complex assembly GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 95
+	Hs
		1355475 DDX20_HUMAN (1-824): 0: 727: 100.00		LSM4_HUMAN (1-87): 3.25e-32: 110: 32.58
+	Hs
		912395 DDX20_HUMAN (1-824): 0: 727: 100.00		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		912750 DDX20_HUMAN (1-824): 0: 727: 100.00		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		911990 DDX20_HUMAN (1-824): 0: 727: 100.00		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		640677 DDX6_HUMAN (25-444): 7.61e-164: 486: 32.62		LSM4_HUMAN (1-87): 3.25e-32: 110: 32.58
+	Sc
		746288 DHH1_YEAST (37-450): 3.88e-165: 490: 35.73		LSM2_YEAST (1-95): 2.94e-31: 106: 63.16
+	Sc
		761950 DHH1_YEAST (37-450): 3.88e-165: 490: 35.73		LSM4_YEAST (1-83): 6.73e-22: 85.7: 22.83
+	Hs
		911887 DDX42_HUMAN (9-756): 3.7e-132: 418: 17.75		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		571387 DDX5_HUMAN (13-488): 1.13e-131: 407: 22.70		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		757541 IF4A3_HUMAN (38-444): 2.03e-124: 381: 32.84		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		757543 IF4A3_HUMAN (38-444): 2.03e-124: 381: 32.84		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		757540 IF4A3_HUMAN (38-444): 2.03e-124: 381: 32.84		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		911833 DX39B_HUMAN (64-440): 3.19e-67: 231: 36.05		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43