HitPredict

Interactor 1: UBP25 (Q9UHP3)
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25)
Gene: USP25

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	28619731, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 1294
+	Mm
		1113670 UBP48_MOUSE (157-406): 1.11e-64: 240: 25.86		V9GX76_MOUSE (1-1294): 0: 1075: 95.98
+	Hs
		1350122 UBP36_HUMAN (560-684): 1.95e-11: 70.7: 22.84		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1273743 USP9X_HUMAN (142-459): 2.23e-67: 250: 20.22		MYO10_HUMAN (3-997): 0: 878: 30.44
+	Mm
		883712 UBP25_MOUSE (1-1055): 0: 1023: 93.85		MYH9_MOUSE (765-1178): 3.23e-12: 73.5: 14.05
+	Hs
		1161776 UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78		MYO7B_HUMAN (4-863): 0: 883: 30.08
+	Hs
		1273898 UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78		MYO10_HUMAN (3-997): 0: 878: 30.44
+	Mm
		1113556 UBP48_MOUSE (157-406): 1.11e-64: 240: 25.86		MYO5A_MOUSE (710-1184): 1.64e-18: 94.2: 8.65
+	Mm
		1113526 UBP48_MOUSE (157-406): 1.11e-64: 240: 25.86		MYH9_MOUSE (765-1178): 3.23e-12: 73.5: 14.05
+	Mm
		93872 UBP48_MOUSE (157-406): 1.11e-64: 240: 25.86		E9QPE7_MOUSE (831-1100): 1.13e-10: 68.5: 15.05
+	Mm
		1113446 UBP48_MOUSE (157-406): 1.11e-64: 240: 25.86		MYH10_MOUSE (762-1135): 6.81e-09: 62.8: 16.00
+	Sc
		585344 UBP15_YEAST (146-421): 8.56e-59: 223: 22.73		MYO2_YEAST (928-1223): 4.47e-10: 66.5: 9.09
+	Hs
		528398 UBP24_HUMAN (158-405): 3.95e-35: 148: 21.40		MYH6_HUMAN (760-1113): 5.54e-10: 66.2: 18.89
+	Hs
		724949 UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		1273988 UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78		MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72
+	Hs
		271039 UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		725051 UBP36_HUMAN (560-684): 1.95e-11: 70.7: 22.84		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70