HitPredict

Interactor 1: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 559 Hs			1 955
+	Hs
		1054689 RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		1054625 RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1355616 PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1191705 PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		1264818 PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		1054673 RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1054314 RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1020354 ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1288650 PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		965152 PABP3_HUMAN (479-559): 6.17e-13: 73.4: 19.75		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		516749 PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1031405 PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Hs
		516609 PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20