HitPredict

Interactor 1: EVL (Q9UI08)
Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like)
Gene: EVL

Interactor 2: WASF2 (Q9Y6W5)
Actin-binding protein WASF2 (Protein WAVE-2) (Verprolin homology domain-containing protein 2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2)
Gene: WASF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0017124 - SH3 domain binding GO:0030027 - lamellipodium
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 498
+	Hs
		840622 VASP_HUMAN (1-412): 5.97e-57: 193: 41.59		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Hs
		1191642 SPRE1_HUMAN (2-165): 1.31e-48: 173: 26.74		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Hs
		1345520 HOME3_HUMAN (3-169): 1.07e-37: 141: 20.00		WASF2_HUMAN (1-498): 3.76e-64: 218: 100.00
+	Hs
		203214 VASP_HUMAN (1-412): 5.97e-57: 193: 41.59		SYNJ1_HUMAN (36-496): 2.09e-41: 161: 13.30
+	Mm
		1247005 HOME1_MOUSE (1-197): 6.93e-55: 187: 19.50		WASF1_MOUSE (1-496): 3.12e-42: 160: 43.19
+	Dm
		94637 ENA_DROME (2-386): 1.01e-40: 156: 24.68		F2FB81_DROME (1-245): 9.78e-42: 160: 41.53
+	Dm
		113976 M9PB30_DROME (95-363): 1.2e-12: 72.4: 13.04		M9PB30_DROME (78-398): 6.3e-10: 64.3: 13.71