HitPredict

Interactor 1: CTNA3 (Q9UI47)
Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein)
Gene: CTNNA3

Interactor 2: PKP3 (Q9Y446)
Plakophilin-3
Gene: PKP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.60	0.565

Property	Details
Experiments	30482882, 23136403
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005912 - adherens junction GO:0030057 - desmosome GO:0045296 - cadherin binding GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 895 Hs			1 797
+	Hs
		1304585 CTNA3_HUMAN (1-895): 0: 1016: 100.00		PKP4_HUMAN (10-797): 1.27e-141: 449: 25.49
+	Hs
		119788 CTNA3_HUMAN (1-895): 0: 1016: 100.00		ARVC_HUMAN (26-794): 2.2e-139: 437: 25.22
+	Hs
		716755 CTNA1_HUMAN (7-891): 0: 992: 59.40		PKP4_HUMAN (10-797): 1.27e-141: 449: 25.49
+	Hs
		1307400 CTNA3_HUMAN (1-895): 0: 1016: 100.00		PKP2_HUMAN (16-796): 6.3e-135: 423: 26.56
+	Hs
		239222 CTNA3_HUMAN (1-895): 0: 1016: 100.00		CTND1_HUMAN (24-794): 7.12e-130: 412: 24.50
+	Hs
		716759 CTNA1_HUMAN (7-891): 0: 992: 59.40		PKP2_HUMAN (16-796): 6.3e-135: 423: 26.56
+	Hs
		239065 CTNA1_HUMAN (7-891): 0: 992: 59.40		CTND1_HUMAN (24-794): 7.12e-130: 412: 24.50
+	Hs
		717407 CTNA3_HUMAN (1-895): 0: 1016: 100.00		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11
+	Hs
		640706 CTNA2_HUMAN (2-891): 0: 1002: 57.66		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11
+	Hs
		716609 CTNA1_HUMAN (7-891): 0: 992: 59.40		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11
+	Mm
		640689 CTNA1_MOUSE (7-891): 0: 986: 59.28		CTNB1_MOUSE (101-739): 2.27e-106: 345: 16.11
+	Hs
		542474 CTNA3_HUMAN (1-895): 0: 1016: 100.00		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Hs
		542192 CTNA2_HUMAN (2-891): 0: 1002: 57.66		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Hs
		542214 CTNA1_HUMAN (7-891): 0: 992: 59.40		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Mm
		640690 CTNA1_MOUSE (7-891): 0: 986: 59.28		PLAK_MOUSE (114-739): 1.83e-92: 307: 15.28
+	Dm
		578618 CTNA_DROME (7-891): 0: 930: 51.39		ARM_DROME (92-793): 1e-98: 327: 14.59
+	Ce
		954162 HMP1_CAEEL (9-894): 0: 808: 36.54		JAC1_CAEEL (191-796): 2.22e-100: 339: 24.71
+	Hs
		626280 CTNA3_HUMAN (1-895): 0: 1016: 100.00		APC_HUMAN (329-537): 1.78e-09: 63.7: 23.85
+	Hs
		626059 CTNA1_HUMAN (7-891): 0: 992: 59.40		APC_HUMAN (329-537): 1.78e-09: 63.7: 23.85
+	Rn
		1137286 Q5U302_RAT (4-891): 0: 978: 58.95		CTNB1_RAT (142-506): 1.72e-10: 66.6: 14.10