HitPredict

Interactor 1: DAPK2 (Q9UIK4)
Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)
Gene: DAPK2

Interactor 2: DAPK2 (Q9UIK4)
Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1)
Gene: DAPK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 10376525, 10629061, 11230133
Identification Methods enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 16 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 370
Hs

1 370
+ Hs
+ Gm
+ At
+ At
+ Hs
+ Mm
+ Rn
+ At
+ At
+ Ce
+ At
+ Dm
+ Hs
+ Hs
+ At
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+ Hs

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Last updated: 15 Jul 2024