HitPredict - High confidence protein-protein interactions

Interactor 1: PLXA1 (Q9UIW2)
Plexin-A1 (Semaphorin receptor NOV)
Gene: PLXNA1

Interactor 2: PLXA1 (Q9UIW2)
Plexin-A1 (Semaphorin receptor NOV)
Gene: PLXNA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.829

Property	Details
Experiments	25315821, 11239433, 15187088
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Plexin_cytopl~Plexin_cytopl, Plexin_RBD~Plexin_RBD, PSI~Sema, PSI~TIG, PSI~TIG_2, PSI~TIG_plexin, Sema~Sema, Sema~TIG, Sema~TIG_plexin, TIG~TIG, TIG_plexin~TIG_plexin
Common GO terms	GO:0002116 - semaphorin receptor complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007162 - negative regulation of cell adhesion and 11 others more... GO:0008360 - regulation of cell shape GO:0014910 - regulation of smooth muscle cell migration GO:0017154 - semaphorin receptor activity GO:0021628 - olfactory nerve formation GO:0021828 - gonadotrophin-releasing hormone neuronal migration to the hypothalamus GO:0030334 - regulation of cell migration GO:0050772 - positive regulation of axonogenesis GO:0060666 - dichotomous subdivision of terminal units involved in salivary gland branching GO:0070062 - extracellular exosome GO:1902287 - semaphorin-plexin signaling pathway involved in axon guidance GO:1990138 - neuron projection extension
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1	1896
Hs

1	1896

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Last updated: 15 Jul 2024