HitPredict

Interactor 1: NAGK (Q9UJ70)
N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase) (Muramyl dipeptide kinase) (EC 2.7.1.-) (N-acetyl-D-mannosamine kinase) (EC 2.7.1.60)
Gene: NAGK

Interactor 2: NAGK (Q9UJ70)
N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase) (Muramyl dipeptide kinase) (EC 2.7.1.-) (N-acetyl-D-mannosamine kinase) (EC 2.7.1.60)
Gene: NAGK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.90	0.835

The method score is based on:

Property	Details
Experiments	25416956, 16189514, 27107012
Identification Methods	two hybrid, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	BcrAD_BadFG~BcrAD_BadFG
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006044 - N-acetylglucosamine metabolic process GO:0006051 - N-acetylmannosamine metabolic process GO:0019262 - N-acetylneuraminate catabolic process and 7 others more... GO:0032495 - response to muramyl dipeptide GO:0042742 - defense response to bacterium GO:0045087 - innate immune response GO:0045127 - N-acetylglucosamine kinase activity GO:0070062 - extracellular exosome GO:0070434 - positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway GO:0160047 - muramyl dipeptide kinase activity
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024