HitPredict

Interactor 1: HOOK1 (Q9UJC3)
Protein Hook homolog 1 (h-hook1) (hHK1)
Gene: HOOK1

Interactor 2: AP4E1 (Q9UPM8)
AP-4 complex subunit epsilon-1 (AP-4 adaptor complex subunit epsilon) (Adaptor-related protein complex 4 subunit epsilon-1) (Epsilon subunit of AP-4) (Epsilon-adaptin)
Gene: AP4E1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	28718761, 32073997
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 1137
+	Hs
		1202483 HOOK3_HUMAN (216-727): 3.62e-13: 75.1: 12.69		AP4E1_HUMAN (1-1137): 0: 1063: 100.00
+	Hs
		1289576 HOOK2_HUMAN (306-714): 5.05e-09: 61.7: 13.01		AP4E1_HUMAN (1-1137): 0: 1063: 100.00
+	Hs
		925885 GRDN_HUMAN (160-728): 9.47e-25: 113: 14.22		AP2B1_HUMAN (59-902): 0: 636: 14.14
+	Hs
		724758 MYH9_HUMAN (1-550): 5.58e-23: 107: 13.78		AP2B1_HUMAN (59-902): 0: 636: 14.14
+	Hs
		321498 MYH9_HUMAN (1-550): 5.58e-23: 107: 13.78		AP2A1_HUMAN (25-913): 0: 623: 18.70
+	Hs
		321651 MYO5C_HUMAN (183-653): 1.91e-18: 92.7: 15.72		AP2A1_HUMAN (25-913): 0: 623: 18.70
+	Hs
		321607 MY18A_HUMAN (247-697): 1.83e-10: 66.9: 17.26		AP2A1_HUMAN (25-913): 0: 623: 18.70