HitPredict

Interactor 1: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 25416956, 32296183, 11331580, 11806752, unassigned1304, 22829933
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX, zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005737 - cytoplasm
GO:0005874 - microtubule
GO:0008017 - microtubule binding
GO:0008270 - zinc ion binding
and 15 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024